Determinants of Breast Cancer Screening Adherence During the COVID-19 Pandemic in a Cohort at Increased Inherited Cancer Risk in the United States

Cancer Control. 2024 Jan-Dec:31:10732748241272727. doi: 10.1177/10732748241272727.

Abstract

Background: We examined neighborhood characteristics concerning breast cancer screening annual adherence during the COVID-19 pandemic.

Methods: We analyzed 6673 female patients aged 40 or older at increased inherited cancer risk in 2 large health care systems (NYU Langone Health [NYULH] and the University of Utah Health [UHealth]). Multinomial models were used to identify predictors of mammogram screening groups (non-adherent, pre-pandemic adherent, pandemic period adherent) in comparison to adherent females. Potential determinants included sociodemographic characteristics and neighborhood factors.

Results: Comparing each cancer group in reference to the adherent group, a reduced likelihood of being non-adherent was associated with older age (OR: 0.97, 95% CI: 0.95, 0.99), a greater number of relatives with cancer (OR: 0.80, 95% CI: 0.75, 0.86), and being seen at NYULH study site (OR: 0.42, 95% CI: 0.29, 0.60). More relatives with cancer were correlated with a lesser likelihood of being pandemic period adherent (OR: 0.89, 95% CI: 0.81, 0.97). A lower likelihood of being pre-pandemic adherent was seen in areas with less education (OR: 0.77, 95% CI: 0.62, 0.96) and NYULH study site (OR: 0.35, 95% CI: 0.22, 0.55). Finally, greater neighborhood deprivation (OR: 1.47, 95% CI: 1.08, 2.01) was associated with being non-adherent.

Conclusion: Breast screening during the COVID-19 pandemic was associated with being older, having more relatives with cancer, residing in areas with less educational attainment, and being seen at NYULH; non-adherence was linked with greater neighborhood deprivation. These findings may mitigate risk of clinically important screening delays at times of disruptions in a population at greater risk for breast cancer.

Keywords: COVID-19; cancer screening; education; electronic health records; health inequities; inherited risk; mammograms; neighborhood barriers; racial disparities; structural barriers.

Plain language summary

Breast Cancer Screening Adherence in the US During COVID-19: We examined predictors of breast cancer screening adherence during COVID-19 at two large healthcare systems. Adherence was associated with older age, having more relatives with a cancer history, and living in areas with less educational attainment. Nonadherence was associated with greater neighborhood deprivation.

MeSH terms

  • Adult
  • Aged
  • Breast Neoplasms* / diagnosis
  • Breast Neoplasms* / epidemiology
  • Breast Neoplasms* / genetics
  • COVID-19* / epidemiology
  • Early Detection of Cancer* / statistics & numerical data
  • Female
  • Genetic Predisposition to Disease
  • Humans
  • Mammography / statistics & numerical data
  • Middle Aged
  • Patient Compliance / statistics & numerical data
  • Risk Factors
  • SARS-CoV-2
  • United States / epidemiology