Elevated liver function tests in infants exposed to elexacaftor-tezacaftor-ivacaftor in utero and while breastfeeding - Case reports

Theresa Jane Kolaczkowski; Amanda Bevan; Julian Legg; Jay Self; Mark Allenby

doi:10.1016/j.jcf.2024.09.025

Elevated liver function tests in infants exposed to elexacaftor-tezacaftor-ivacaftor in utero and while breastfeeding - Case reports

J Cyst Fibros. 2024 Oct 17:S1569-1993(24)01793-4. doi: 10.1016/j.jcf.2024.09.025. Online ahead of print.

Authors

Theresa Jane Kolaczkowski¹, Amanda Bevan², Julian Legg², Jay Self³, Mark Allenby⁴

Affiliations

¹ Wessex Adult Cystic Fibrosis Service, University Hospital Southampton NHS Foundation Trust, Southampton, UK. Electronic address: theresa.kolaczkowski@uhs.nhs.uk.
² Department of Paediatrics, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
³ Ophthalmology department, University Hospital Southampton, Southampton, UK; Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
⁴ Wessex Adult Cystic Fibrosis Service, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

PMID: 39424519
DOI: 10.1016/j.jcf.2024.09.025

No abstract available

Keywords: Breast milk; Breastfeeding; Cataract; Drug-induced liver injury; Elexacaftor-tezacaftor-ivacaftor; Liver function test; Pregnancy; Pregnant.

Publication types

Case Reports