Skin Imaging of Juvenile Xanthogranuloma: In Vivo Diagnosis by Line-Field Confocal Optical Coherence Tomography

Gerardo Palmisano; Simone Cappilli; Enrico Bocchino; Alessandro Di Stefani; Ketty Peris

doi:10.1111/pde.15786

Skin Imaging of Juvenile Xanthogranuloma: In Vivo Diagnosis by Line-Field Confocal Optical Coherence Tomography

Pediatr Dermatol. 2024 Oct 24. doi: 10.1111/pde.15786. Online ahead of print.

Authors

Gerardo Palmisano^{1

2}, Simone Cappilli^{1

2}, Enrico Bocchino^{1

2}, Alessandro Di Stefani^{1

2}, Ketty Peris^{1

2}

Affiliations

¹ Dermatologia, Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.
² UOC di Dermatologia, Dipartimento Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy.

PMID: 39445503
DOI: 10.1111/pde.15786

Abstract

A 15-year-old boy presented with a yellowish, asymptomatic nodule on the left forearm, which developed in the last year. A diagnosis of juvenile xanthogranuloma was confirmed with histopathology. Line-field confocal optical coherence tomography (LC-OCT), a new skin imaging technique, was performed prior to surgery, showing a strong correspondence with histopathological sections. As juvenile xanthogranuloma is a benign disorder of the pediatric age, LC-OCT may represent an alternative to surgery for achieving a fast diagnosis in uncertain cases.

Keywords: clinical dermatology; diagnosis; diagnostic imaging; juvenile xanthogranuloma; pediatric dermatology.

Publication types

Case Reports