Environmental Vibrio cholerae Strains Harboring Cholera Toxin and Vibrio Pathogenicity Island 1, Nigeria, 2008-2015

Emerg Infect Dis. 2024 Nov;30(11):2441-2444. doi: 10.3201/eid3011.240495.

Abstract

Analysis of clinical and environmental Vibrio cholerae O1 strains obtained during 2008-2015 in Nigeria showed that lineages Afr9 and Afr12 carrying cholera toxin and Vibrio pathogenicity island 1 can be isolated from water. Our findings raise concerns about the role of the environment in maintenance and emergence of cholera outbreaks in Nigeria.

Keywords: Nigeria; Vibrio cholerae; Vibrio cholerae lineages; antimicrobial resistance; bacteria; diarrhea; enteric infections; human infection; outbreak; virulence; waterborne infection.

Publication types

  • Historical Article

MeSH terms

  • Cholera Toxin* / genetics
  • Cholera* / epidemiology
  • Cholera* / microbiology
  • Disease Outbreaks
  • Environmental Microbiology
  • Genomic Islands*
  • History, 21st Century
  • Humans
  • Nigeria / epidemiology
  • Vibrio cholerae / classification
  • Vibrio cholerae / genetics
  • Vibrio cholerae / pathogenicity
  • Vibrio cholerae O1 / classification
  • Vibrio cholerae O1 / genetics
  • Vibrio cholerae O1 / isolation & purification
  • Vibrio cholerae O1 / pathogenicity

Substances

  • Cholera Toxin