[Standardized diagnosis and treatment of immune checkpoint inhibitor-induced thyroid dysfunction]

Zhonghua Nei Ke Za Zhi. 2024 Nov 1;63(11):1116-1119. doi: 10.3760/cma.j.cn112138-20240906-00556.
[Article in Chinese]

Abstract

免疫检查点抑制剂(ICPis)通过阻断免疫抑制分子,促进效应T细胞发挥杀伤肿瘤细胞的作用,抑制肿瘤的生长和扩散。甲状腺损伤是肿瘤患者接受ICPis治疗过程中常见的免疫相关不良反应之一。本文就ICPis致甲状腺损伤的发病机制、临床表现、诊治及随访等方面进行介绍,使内分泌科和肿瘤科医生加强合作,提高ICPis相关甲状腺损伤的诊治水平。.

MeSH terms

  • Humans
  • Immune Checkpoint Inhibitors* / adverse effects
  • Neoplasms / drug therapy
  • Thyroid Diseases* / chemically induced
  • Thyroid Diseases* / diagnosis
  • Thyroid Diseases* / therapy
  • Thyroid Gland / immunology

Substances

  • Immune Checkpoint Inhibitors