Abstract
免疫检查点抑制剂(ICPis)通过阻断免疫抑制分子,促进效应T细胞发挥杀伤肿瘤细胞的作用,抑制肿瘤的生长和扩散。甲状腺损伤是肿瘤患者接受ICPis治疗过程中常见的免疫相关不良反应之一。本文就ICPis致甲状腺损伤的发病机制、临床表现、诊治及随访等方面进行介绍,使内分泌科和肿瘤科医生加强合作,提高ICPis相关甲状腺损伤的诊治水平。.
MeSH terms
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Humans
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Immune Checkpoint Inhibitors* / adverse effects
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Neoplasms / drug therapy
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Thyroid Diseases* / chemically induced
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Thyroid Diseases* / diagnosis
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Thyroid Diseases* / therapy
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Thyroid Gland / immunology
Substances
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Immune Checkpoint Inhibitors