High Retention and Adherence with Rapid Long-Acting Injectable PrEP Implementation in an Urban Safety-Net Clinic Population

Matthew A Spinelli; Ezra Bisom-Rapp; Megan J Heise; Christina Camp; Ayesha Appa; Albert Y Liu; Kevin Sassaman; Mary Shiels; Francis Mayorga-Munoz; Anthonia Chimezie; Janet Nguyen; Jon Oskarsson; Monica Gandhi

doi:10.1093/cid/ciae531

High Retention and Adherence with Rapid Long-Acting Injectable PrEP Implementation in an Urban Safety-Net Clinic Population

Clin Infect Dis. 2024 Nov 1:ciae531. doi: 10.1093/cid/ciae531. Online ahead of print.

Affiliations

¹ Division of HIV, ID, and Global Medicine, University of California, San Francisco, United States.
² Department of Medicine, University of California, San Francisco, United States.
³ Bridge HIV, San Francisco Department of Public Health, United States.

PMID: 39484783
DOI: 10.1093/cid/ciae531

Abstract

In a low-barrier long-acting PrEP program in a safety-net setting, permitting same-day or next-day initiation, 85% of injections were on-time, and six-month retention was 83%, surpassing outcomes from most previously-reported oral PrEP studies. With drop-in, wrap-around services, similar retention among housing-insecure populations was seen. Long-acting PrEP expansion is urgently needed.

Keywords: Cabotegravir; Low-Barrier; PrEP; Rapid; Retention.

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