Clinical and radiographic characteristics of traumatic brain injury patients undergoing endovascular rescue for posttraumatic vasospasm

Kasra Khatibi; Lucido Luciano Ponce Mejia; Hamidreza Saber; Naoki Kaneko; Satoshi Tateshima; May Nour; Geoffrey Philip Colby; Reza Jahan; Manual Buitrago-Blanco; Paul Vespa; Gary Duckwiler; Viktor Szeder

doi:10.4103/bc.bc_117_23

Clinical and radiographic characteristics of traumatic brain injury patients undergoing endovascular rescue for posttraumatic vasospasm

Brain Circ. 2024 Sep 26;10(3):273-276. doi: 10.4103/bc.bc_117_23. eCollection 2024 Jul-Sep.

Authors

Affiliations

¹ Department of Neurosurgery, University of Southern California, Los Angeles, California, United States.
² Department of Neurosurgery, Louisiana State University, New Orleans, LA, United States.
³ Department of Neurology, University of Texas Austin, Austin, TX, United States.
⁴ Department of Radiology, University of California Los Angeles, Los Angeles, California, United States.
⁵ Department of Neurology, University of California Los Angeles, Los Angeles, California, United States.
⁶ Department of Neurosurgery, University of California Los Angeles, Los Angeles, California, United States.

Abstract

Background: Cerebral vasospasm is a serious sequela of traumatic brain injury (TBI) which leads to further neurologic injury subsequent to the initial trauma. The natural history and associated risk factors are not well understood. The objective of this study is to evaluate the clinical and radiographic characteristics of patients with TBI.

Methods: This is a descriptive case series of all patients with TBI who underwent cerebral angiogram for evaluation and rescue therapy for posttraumatic arterial vasospasm (PTV) between October 2017 and November 2019. The association of clinical and radiographic characteristics with cumulative severity of angiographic vasospasm was evaluated. The clinical characteristics comprised of age, sex, Glascow Coma Scale (GCS) and need for surgery. The radiographic characteristics were presence of subarachnoid hemorrhage (SAH), location of SAH, presence of contusion, presence of subdural hemorrhage (SDH), and presence of pseudoaneurysm.

Results: Twenty-two patients with PTV were identified requiring 69 cerebral angiograms (mean: 3.2; range: 1-9 angiograms per patient) during this period. The average age upon presentation was 40 years old, 81% of the patients were male sex, and the average GCS was 6.8. 67% of the patients underwent craniotomy or craniectomy. All patients had SAH, although only 60% had cisternal SAH. Parenchymal contusion was noted on 90% as well as SDH in 90%. The PTV was noted between 3 and 19 days after trauma. There was more vasospasm involving proximal arteries and higher severity of vasospasm in patients with cisternal SAH. Otherwise, there was no strong association between the clinical or radiographic characteristics and cumulative severity noted on the angiograms for each patient.

Conclusion: Posttraumatic vasospasm can be detected as early as posttrauma day 3-19 in patients with TBI and SAH. The absence of cisternal SAH does not rule out the occurrence of the vasospasm during the course of treatment.

Keywords: Subarachnoid hemorrhage; traumatic brain injury; vasospasm.