Leveraging digital tools to enhance diversity and inclusion in clinical trial recruitment

Front Public Health. 2024 Oct 28:12:1483367. doi: 10.3389/fpubh.2024.1483367. eCollection 2024.

Abstract

Clinical research is pivotal in assessing the safety and efficacy of new treatments in healthcare. However, the success of such research depends on the inclusion of a diverse and representative participant sample, which is currently lacking. This lack of diversity in biomedical research participants has significant repercussions, limiting the real-world applicability and accessibility of medical interventions, especially for underrepresented groups. Barriers to diverse participation include historical mistrust, logistical challenges, and financial constraints. Recent guidelines by government agencies and funding bodies emphasize the need for diversity in clinical trials, but specific strategies for inclusive recruitment are often lacking. This paper explores the use of digital methods to enhance diversity and inclusion in research recruitment. Digital tools, such as electronic medical records, social media, research registries, and mobile applications, offer promising opportunities for reaching diverse populations. Strategies include culturally tailored messaging, collaborations with community organizations, and the use of SEO to improve visibility and engagement. However, challenges such as privacy concerns, digital literacy gaps, and ethical considerations must be addressed. The promotion of diversity in clinical research recruitment is crucial for advancing health equity. By leveraging digital tools and adopting inclusive strategies, study teams can improve the diversity of study participants, ultimately leading to more applicable and equitable healthcare outcomes.

Keywords: digital health; digital methods; diverse population; diversity in clinical research; health equity; inclusive recruitment; social media.

MeSH terms

  • Biomedical Research
  • Clinical Trials as Topic*
  • Cultural Diversity*
  • Electronic Health Records
  • Humans
  • Mobile Applications
  • Patient Selection*
  • Social Media

Grants and funding

The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This work was supported by the American Heart Association (953550) as part of the Strategically Focused Research Network on the Science of Diversity in Clinical Trials. CONNECT is a project of the IMPACT (Improving Participation Among diverse populations in Cardiovascular clinical Trials) Center (946222). It was supported by the Johns Hopkins Institute for Clinical and Translational Research (ICTR), which is funded in part by the National Center for Advancing Translational Sciences (NCATS; Grant 1UM1TR004926-01), a component of the NIH and the NIH Roadmap for Medical Research, and supported by the NIH. The research was also supported by the NIH Community Engagement Alliance (CEAL) Initiative (Award OT2HL161612).