The Von-Meyenburg complex, also known as biliary hamartomas, are benign malformations of the intrahepatic bile ducts. Typically identified incidentally, these lesions are generally asymptomatic and have no pathological significance. However, their imaging characteristics can mimic malignancy, and they possess a rare potential for progression to hepatocellular carcinoma. Familial clusters suggest a potential genetic basis, with the polycystic kidney and hepatic disease 1 (PKHD1) gene most commonly associated.
Keywords: biliary hamartomas; gamma-glutamyl transferase (ggt); genetic predisposition; hepatobiliary contrast mri; hepatocellular carcinoma (hcc); liver imaging; liver lesions; non-alcoholic fatty liver disease (nafld); polycystic kidney and hepatic disease 1 (pkhd1); von-meyenburg complex.
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