Ictal asystole is a rare complication of epilepsy

Ugeskr Laeger. 2024 Nov 4;186(45):V04240297. doi: 10.61409/V04240297.
[Article in Danish]

Abstract

Ictal bradyarrhythmia (IB) and ictal asystole (IA) are rare complications of epilepsy. Onset latency of IB/IA implicates central nervous parasympathetic pathways, causing asystole, subsequent cerebral hypoxaemia, and potentially inducing a paradoxal, therapeutic effect by terminating both the seizure and the IA. This is a case report of a 68-year-old woman with mesial temporal lobe epilepsy and hippocampal sclerosis and IA. Association of IB/IA and sudden unexpected death in epilepsy lacks evidence and pacemaker therapy is rarely indicated. Treatment aims to minimize seizures and reduce the risk of falls.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Bradycardia / diagnosis
  • Bradycardia / etiology
  • Bradycardia / therapy
  • Electroencephalography
  • Epilepsy, Temporal Lobe* / complications
  • Female
  • Heart Arrest* / etiology
  • Heart Arrest* / therapy
  • Hippocampus / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Sclerosis