Electrochemical Nanosensor-Based Emerging Point-Of-Care Tools: Progress and Prospects

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2024 Nov-Dec;16(6):e2002. doi: 10.1002/wnan.2002.

Abstract

Early detection of disease remains a crucial challenge in medicine. Delayed diagnosis often leads to limited treatment options, increased disease progression, and unfortunately, even death in some cases. To address this, the need for rapid, cost-effective, and noninvasive diagnostic tools is paramount. In recent years, electrochemical nanosensor-based point-of-care diagnostic tools have emerged as promising tools for various fields, with significant interest in their biological and chemical applications. These tiny sensors, utilizing nanoparticles and chemical agents, can detect and monitor physical components like disease biomarkers at the nanoscale, offering a unique advantage rarely found in other diagnostic methods. This unprecedented sensitivity has made them highly sought-after tools for biological applications, particularly in disease diagnosis. This review focuses specifically on electrochemical nanosensors and their potential as diagnostic tools in medicine. We will delve into their properties, applications, current advancements, and existing limitations.

Keywords: diagnostics; electrochemistry; nanoparticles; nanosensors.

Publication types

  • Review

MeSH terms

  • Animals
  • Biomarkers / analysis
  • Biosensing Techniques*
  • Electrochemical Techniques*
  • Humans
  • Nanoparticles / chemistry
  • Nanotechnology
  • Point-of-Care Systems*

Substances

  • Biomarkers