Association of Neonatal and Maternal Nasal Microbiome Among Neonates in the Intensive Care Unit

Shaoming Xiao; Wei Zhou; Ryan Caldwell; Slade Decker; Julia Oh; Aaron M Milstone

doi:10.1093/ofid/ofae644

Association of Neonatal and Maternal Nasal Microbiome Among Neonates in the Intensive Care Unit

Open Forum Infect Dis. 2024 Oct 28;11(11):ofae644. doi: 10.1093/ofid/ofae644. eCollection 2024 Nov.

Authors

Shaoming Xiao¹, Wei Zhou², Ryan Caldwell², Slade Decker¹, Julia Oh², Aaron M Milstone¹

Affiliations

¹ Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
² The Jackson Laboratory, Farmington, Connecticut, USA.

Abstract

The neonatal nasal microbiota may help protect neonates in the neonatal intensive care unit from pathogen colonization and infection. This preliminary study characterized the biodiversity of nasal microbiota comparing neonates in the neonatal intensive care unit and their mothers, highlighting the potential of strain sharing between mother-neonate pairs.

Keywords: anterior nares; metagenomics; microbiome; neonates; staphylococcus aureus.