Pioneering Hand Hygiene: Ignaz Semmelweis and the Fight Against Puerperal Fever

Cureus. 2024 Oct 17;16(10):e71689. doi: 10.7759/cureus.71689. eCollection 2024 Oct.

Abstract

Hungarian physician Ignaz Semmelweis (1818-1865) revolutionized medical practice through his introduction of antiseptic procedures. This breakthrough disrupted the chain of infection among new mothers and their infants, leading to dramatically reduced mortality rates from puerperal fever across continental Europe. Semmelweis faced significant resistance and disbelief when he argued through meticulous, empirically-based evidence that proper hand hygiene may prevent infection. Semmelweis' pioneering work on infection prevention remains highly relevant even today, as evidenced by contemporary practices aimed at controlling the spread of disease and improving patient safety through improved hygiene. In this article, we look into the key moments in Semmelweis's life that led to his revolutionary discoveries as well as oppositions against them and his lasting impact on modern medicine.

Keywords: antiseptic procedures; chlorinated lime; germ theory; hand hygiene; historical vignette; ignaz semmelweis; infection control; maternal mortality; medical innovation; puerperal fever.

Publication types

  • Review