Characteristics and outcomes of myocardial infarction among burn patients: A nationwide analysis

Ramy Sedhom; Mohamed Khedr; Rafail Beshai; Emmanouil S Brilakis; Mir B Basir; Khaldoon Alaswad; Liset Stoletniy; Dmitry Abramov; Aditya Bharadwaj; Michael Megaly

doi:10.1016/j.burns.2024.107313

Characteristics and outcomes of myocardial infarction among burn patients: A nationwide analysis

Burns. 2024 Nov 10;51(1):107313. doi: 10.1016/j.burns.2024.107313. Online ahead of print.

Authors

Affiliations

¹ Division of Cardiology, Loma Linda University Medical Center, Loma Linda, CA, USA. Electronic address: ramysedhom@hotmail.com.
² Faculty of Medicine, Menoufia University, Menoufia, Egypt.
³ Division of Internal Medicine, Jefferson Health, Washington Township, NJ, USA.
⁴ Division of Cardiology, Minneapolis Heart Institute, Minneapolis, MN, USA.
⁵ Division of Cardiology, Henry Ford Hospital, Detroit, MI, USA.
⁶ Division of Cardiology, Loma Linda University Medical Center, Loma Linda, CA, USA.
⁷ Ascension St John Heart and Vascular Institute, Tulsa, OK, USA.

PMID: 39561551
DOI: 10.1016/j.burns.2024.107313

Abstract

Purpose: To examine the characteristics and outcomes of myocardial infarction (MI) among burn patients.

Materials and methods: The Nationwide Readmissions Database was utilized to identify hospitalizations of patients with burns from 2016 to 2020. The main outcome was the difference in all-cause in-hospital mortality between burn patients with and without MI.

Results: Of 200,130 hospitalizations with burns, 1997 (1 %) developed acute MI. Burn patients with MI were older, more likely to be men, and had a higher prevalence of cardiovascular risk factors. Only burns affecting the trunk and respiratory tract, and those affecting > 20 % of body surface area (BSA), were associated with an increased risk of MI. All-cause in-hospital mortality was higher among patients with MI (18.7 % vs. 3 %, adjusted odds ratio (aOR) 4.59, 95 % confidence interval (CI) 3.66, 5.76). Cardiogenic shock, ventricular tachycardia, and stroke rates were higher among patients with MI. Revascularization was associated with lower in-hospital mortality (aOR 0.33, 95 % CI 0.17, 0.64) CONCLUSIONS: The incidence of MI in burn patients is low but is associated with high mortality and morbidity. Burns involving the trunk and respiratory tract, and those affecting > 20 % BSA, were associated with an increased risk of MI. Revascularization was associated with lower in-hospital mortality.

Keywords: Burn; Myocardial infarction.