Biomarkers of Auditory-Verbal Hallucinations

Adv Neurobiol. 2024:40:665-681. doi: 10.1007/978-3-031-69491-2_22.

Abstract

Auditory-verbal hallucinations (AVH) are debilitating symptoms experienced by those diagnosed with psychosis as well as many other neurological and psychiatric disorders. Critical to supporting individuals with AVH is identifying biomarkers that serve to track changes in brain states that put individuals at risk for developing or worsening of symptoms. There has been substantial literature identifying neural areas to track over time that may prove to be effective clinical tools. The efficacy of these tools has been bolstered when considering them under mechanistic accounts of AVH. In this chapter, we explore the literature that connects mechanistic theories and structurally based models of AVH and the potential biomarkers derived from this research.

Publication types

  • Review

MeSH terms

  • Biomarkers* / metabolism
  • Brain / metabolism
  • Brain / physiopathology
  • Hallucinations* / physiopathology
  • Humans
  • Psychotic Disorders / metabolism
  • Psychotic Disorders / physiopathology
  • Schizophrenia / metabolism
  • Schizophrenia / physiopathology

Substances

  • Biomarkers