Ancient genomes from the Tang Dynasty capital reveal the genetic legacy of trans-Eurasian communication at the eastern end of Silk Road

BMC Biol. 2024 Nov 20;22(1):267. doi: 10.1186/s12915-024-02068-9.

Abstract

Background: Ancient Chang'an in the Tang Dynasty (618-907 AD) was one of the world's largest and most populated cities and acted as the eastern end of the world-famous Silk Road. However, little is known about the genetics of Chang'an people and whether the Western Regions-related gene flows have been prevalent in this cosmopolitan city.

Results: Here, we present seven genomes from Xingfulindai (XFLD) sites dating to the Tang Dynasty in Chang'an. We observed that four of seven XFLD individuals (XFLD_1) were genetically homogenous with the Late Neolithic Wadian, Pingliangtai, and Haojiatai populations from the middle reaches of the Yellow River Basin (YR_LN), with no genetic influence from the Western Eurasian or other non-Yellow River-related lineages. The remaining three XFLD individuals were a mixture of YR_LN-related ancestry and ~ 3-15% Western Eurasian-related ancestry. Mixtures of XFLD_1 and Western Eurasian-related ancestry drove the main gradient of genetic variation in northern and central Shaanxi Province today.

Conclusions: Our study underlined the widespread distribution of the YR_LN-related ancestry alongside the Silk Road within the territory of China during the historical era and provided direct evidence of trans-Eurasian communication in Chang'an from a genetic perspective.

Keywords: Ancient Chang’an; Ancient DNA; East Asia; Neolithic middle Yellow River-related ancestry; Population history; Silk Road; Tang Dynasty; Western-Eastern admixture.

Publication types

  • Historical Article

MeSH terms

  • Asian People / genetics
  • China
  • DNA, Ancient / analysis
  • Gene Flow
  • Genetic Variation
  • Genome, Human*
  • History, Ancient
  • Human Migration / history
  • Humans

Substances

  • DNA, Ancient