Bi-MOF-based point-of-care testing paper for dual-mode detection of H2S

Jingya Zhou; Xia Gao; Xiying Chen; Hanyue Sun; Xian Li; Liyu Shi; Yaqing Liu

doi:10.1016/j.bios.2024.116934

Bi-MOF-based point-of-care testing paper for dual-mode detection of H₂S

Biosens Bioelectron. 2024 Nov 16:270:116934. doi: 10.1016/j.bios.2024.116934. Online ahead of print.

Authors

Jingya Zhou¹, Xia Gao¹, Xiying Chen¹, Hanyue Sun¹, Xian Li¹, Liyu Shi¹, Yaqing Liu²

Affiliations

¹ State Key Laboratory of Food Nutrition and Safety, College of Food Science and Engineering, Tianjin Key Laboratory of Food Quality and Health, Tianjin University of Science and Technology, Tianjin, 300457, PR China.
² State Key Laboratory of Food Nutrition and Safety, College of Food Science and Engineering, Tianjin Key Laboratory of Food Quality and Health, Tianjin University of Science and Technology, Tianjin, 300457, PR China; School of Life and Health Technology, Dongguan University of Technology, Dongguan, 523808, PR China. Electronic address: liuyaqing@dgut.edu.cn.

PMID: 39579678
DOI: 10.1016/j.bios.2024.116934

Abstract

Hydrogen sulfide (H₂S) is noxious gas and significantly threatens human health. Herein, a Bi-based metal-organic frameworks (Bi-MOFs) based paper analysis device (PAD) has been developed for rapid and effective dual-mode detection of H₂S. The dominant H₂S sensing mechanism is explored. The H₂S can react with Bi-MOF to form bismuth sulfide (Bi₂S₃) MOF (Bi₂S₃-MOF), changing the color of PAD from white to black. The distinguish color change makes it very convenience for visible detection. Meanwhile, the generated Bi₂S₃-MOF exhibits excellent photothermal property, endowing it possible for photothermal imaging detection. In this regard, the PAD boasts a wide linear detection range of 0-40 μM for H₂S with an impressively low limit of detection (LOD) (0.23 μM). The constructed sensing system is demonstrated with outstanding selectivity and storage stability. Satisfied recovery is reached for H₂S detection in diverse real samples. Interestingly, the PAD can be used as intelligent label for assessing meat freshness by monitor H₂S release from meat under different storage temperatures. With integration capabilities of smartphones, the portable and user-friendly PAD offers a simple and rapid solution for on-the-go detection of H₂S in food and environment. The investigation provides an instructive way for environment monitoring and food safety guarding.

Keywords: Bi-MOF; Colorimetric analysis; H(2)S; PADs; Photothermal analysis.