Bimetallic MOF derived electrocatalyst with magnetic alloy nanoparticles confined in S, N-doped carbon nanotubes: A disposable magnetic sensor for simultaneous determination of antibiotics in food

Xinmei Qian; Chunxiang Li; Mingyu Zheng; Jinglun Wang; Haowen Huang; Keqin Deng

doi:10.1016/j.foodchem.2024.142141

Bimetallic MOF derived electrocatalyst with magnetic alloy nanoparticles confined in S, N-doped carbon nanotubes: A disposable magnetic sensor for simultaneous determination of antibiotics in food

Food Chem. 2024 Nov 21;465(Pt 2):142141. doi: 10.1016/j.foodchem.2024.142141. Online ahead of print.

Authors

Xinmei Qian¹, Chunxiang Li², Mingyu Zheng², Jinglun Wang², Haowen Huang³, Keqin Deng⁴

Affiliations

¹ Key Laboratory of Theoretical Organic Chemistry and Function Molecule, Ministry of Education, Hunan University of Science and Technology, Xiangtan 411201, People's Republic of China; Hunan Province College Key Laboratory of Molecular Design and Green Chemistry, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, China.
² Hunan Province College Key Laboratory of Molecular Design and Green Chemistry, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, China.
³ Key Laboratory of Theoretical Organic Chemistry and Function Molecule, Ministry of Education, Hunan University of Science and Technology, Xiangtan 411201, People's Republic of China.
⁴ Key Laboratory of Theoretical Organic Chemistry and Function Molecule, Ministry of Education, Hunan University of Science and Technology, Xiangtan 411201, People's Republic of China. Electronic address: keqindeng@hnust.edu.cn.

PMID: 39581099
DOI: 10.1016/j.foodchem.2024.142141

Abstract

Very few MOF-related derivatives have been applied for sensors. Sensitive analysis of antibiotics in food products is one of the crucial research fields. The work described the synthesis of magnetic electrocatalyst with FeCo alloy nanoparticles confined in S, N-doped bamboo-like carbon nanotubes (FeCo@S,N-CNTs) by using bimetallic MOF as precursor. For comparison, a series of materials were prepared and used to modify screen-printed electrode (SPE). Their electrocatalytic capacities were investigated for the electrochemical reduction of two antibiotics, chloramphenicol (CAP) and nitrofurantoin (NFT). By using cyclic voltammetry (CV) and differential pulse voltammetry (DPV), the magnetic FeCo@S,N-CNTs was found to possess the better electrocatalysis. Using the disposable FeCo@S,N-CNTs/SPE constructed by magnetic control, simultaneous analysis of CAP and NFT was achieved in linear ranges of 0.05-320.0 μM and 0.01-75.0 μM with the limit of detection of 20.0 nM and 3.5 nM, respectively. The real sample detection validated the practicability of FeCo@S,N-CNTs/SPE.

Keywords: Antibiotics; Bimetallic MOF; Confined magnetic alloy nanoparticles; Disposable sensor; S, N-doped carbon nanotubes.