Two genes encoding a bacterial-type ABC transporter function in aluminum tolerance in soybean

Plant Cell Rep. 2024 Nov 25;43(12):295. doi: 10.1007/s00299-024-03381-x.

Abstract

GmABCI5 and GmABCI13 enhance Al tolerance through regulating the composition of root cell wall, and in this process, GmABCI5 and GmABCI13 may act in the form of a complex. Aluminum (Al) toxicity is a major factor limiting plant growth in acidic soils. ATP-binding cassette (ABC) transporters are involved in plant tolerance to various environmental stresses. However, there are few reports on the ABC transporters implicated in soybean tolerance to Al toxicity. Here, we reported that two genes, GmABCI5 and GmABCI13, were involved in Al tolerance in soybean (Glycine max). GmABCI5 and GmABCI13 encode a nucleotide-binding domain and a transmembrane domain of a bacterial-type ABC transporter, respectively. The expression of both GmABCI5 and GmABCI13 was mainly induced by Al in the roots. GmABCI5 was localized at the plasma membrane and also in the cytoplasm and nucleus, while GmABCI13 was only localized at the plasma membrane. Furthermore, GmABCI5 could physically interact with GmABCI13. Overexpression of GmABCI5 or GmABCI13 in Arabidopsis reduced Al accumulation in roots and enhanced Al tolerance. However, expression of GmABCI5 and/or GmABCI13 in yeast cells did not affect Al uptake. Under Al stress, transgenic Arabidopsis lines expressing GmABCI5 or GmABCI13 had lower Al content in root cell walls than wild-type plants. Further analysis showed that Al content in cell wall fractions (pectin and hemicellulose 1) of transgenic lines was significantly lower than that of wild-type plants, which was coincident with the changes of pectin and hemicellulose 1 content under Al stress. These results indicate that GmABCI5 and GmABCI13 form an ABC transporter complex to regulate Al tolerance by affecting the modification of cell wall.

Keywords: ABC transporter; Aluminum tolerance; Cell wall; Soybean.

MeSH terms

  • ATP-Binding Cassette Transporters* / genetics
  • ATP-Binding Cassette Transporters* / metabolism
  • Aluminum* / toxicity
  • Arabidopsis* / drug effects
  • Arabidopsis* / genetics
  • Arabidopsis* / metabolism
  • Cell Membrane / drug effects
  • Cell Membrane / metabolism
  • Cell Wall / drug effects
  • Cell Wall / genetics
  • Cell Wall / metabolism
  • Gene Expression Regulation, Plant* / drug effects
  • Glycine max* / drug effects
  • Glycine max* / genetics
  • Glycine max* / metabolism
  • Plant Proteins* / genetics
  • Plant Proteins* / metabolism
  • Plant Roots* / drug effects
  • Plant Roots* / genetics
  • Plant Roots* / metabolism
  • Plants, Genetically Modified*
  • Stress, Physiological / drug effects
  • Stress, Physiological / genetics

Substances

  • Aluminum
  • ATP-Binding Cassette Transporters
  • Plant Proteins