Assessment of hemodynamic parameters by PiCCO and PAC in patients treated with the Impella CP

Dominik Schmitt; Andreas Schneider; Björn Lengenfelder; Martin Wagner; Daniel Patschan; Benjamin Sasko; Georg Ertl; Stefan Frantz; Oliver Ritter; Dirk Weismann

doi:10.1177/17511437241300909

Assessment of hemodynamic parameters by PiCCO and PAC in patients treated with the Impella CP

J Intensive Care Soc. 2024 Nov 25:17511437241300909. doi: 10.1177/17511437241300909. Online ahead of print.

Authors

Dominik Schmitt¹, Andreas Schneider¹, Björn Lengenfelder^{1

2}, Martin Wagner³, Daniel Patschan^{4

5}, Benjamin Sasko^{4

6}, Georg Ertl^{1

2}, Stefan Frantz^{1

2}, Oliver Ritter^{4

5}, Dirk Weismann^{1

2}

Affiliations

¹ Department of Internal Medicine I, Medical Intensive Care Unit, University Hospital, University of Wuerzburg, Wuerzburg, Germany.
² Comprehensive Heart Failure Center, University of Wuerzburg, Wuerzburg, Germany.
³ Institute of Clinical Epidemiology and Biometry, University of Wuerzburg, Wurzburg, Bayern, Germany.
⁴ Department of Cardiology, Nephrology and Pulmology, Brandenburg Medical School Theodor Fontane University Hospital Brandenburg, Brandenburg, Germany.
⁵ Faculty of Health Sciences (FGW), Joint Faculty of the University of Potsdam, The Brandenburg Medical School Theodor Fontane and the Brandenburg Technical University Cottbus-Senftenberg, Cottbus, Germany.
⁶ Department of Cardiology, Knappschaftskrankenhaus Bottrop, Academic Teaching Hospital, University of Duisburg-Essen, Duisburg, Germany.

Abstract

In 28 patients supported by an Impella pump (Impella CP, Abiomed Inc.^®, Danvers, MA), hemodynamic measurements by PiCCO (PULSION Medical Systems SE^®, Feldkirchen, Germany) and pulmonary artery catheter (PAC or Swan-Ganz Catheter; Edwards Lifescience^®, Unterschleissheim, Germany) were compared. There was a significant positive correlation of cardiac output (CO; r ² = 0.917, p < 0.001), systemic vascular resistance index (SVRI; r ² = 0.904, p < 0.001), stroke volume index (SI; r ² = 0.909, p < 0.001) and left ventricular work index (LCWI; r ² = 0.689, p < 0.001) in PiCCO and PAC measurements under Impella CP support. We conclude, that in patients with left-ventricular Impella support, hemodynamics may be assessentd by PiCCO or PAC.

Keywords: Cardiac hemodynamics; Impella CP; PiCCO system; pulmonary artery catheter.