[Advances in the diagnosis and prognosis of extranodal extension in head and neck squamous cell carcinoma]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Dec;38(12):1190-1194;1202. doi: 10.13201/j.issn.2096-7993.2024.12.020.
[Article in Chinese]

Abstract
in English, Chinese

Objective:The extranodal extension（ENE） is widely found in head and neck squamous cell carcinoma（HNSCC）, which displays the aggressiveness of the tumor and increasing the risk of local recurrence and distant metastasis, so the ENE often has been used as an important indicator of prognosis and treatment. Although the pathologic and radiologic tests are currently the main diagnostic techniques for ENE, there is still a lack of uniform standards. The article reviews the prognostic value, pathologic and radiologic diagnosis of ENE in HNSCC over the recent years.

目的：淋巴结包膜外侵（extranodal extension，ENE）广泛存在于头颈鳞癌中，反映了肿瘤的侵袭性，增加了局部复发和远处转移的风险，具有重要的预后和治疗指导价值。尽管病理组织学和影像学检查是目前用于ENE的主要诊断技术，但仍然缺乏统一的标准。本文对近年来ENE在头颈鳞癌中的预后价值、影像学和病理学诊断的临床应用研究进行综述。.

Keywords: carcinoma,squamous cell; diagnosis; extranodal extension; head and neck neoplasms; prognosis.

Publication types

  • Review
  • English Abstract

MeSH terms

  • Carcinoma, Squamous Cell* / diagnosis
  • Carcinoma, Squamous Cell* / pathology
  • Extranodal Extension
  • Head and Neck Neoplasms* / diagnosis
  • Head and Neck Neoplasms* / pathology
  • Humans
  • Lymphatic Metastasis
  • Neoplasm Recurrence, Local
  • Prognosis
  • Squamous Cell Carcinoma of Head and Neck* / diagnosis
  • Squamous Cell Carcinoma of Head and Neck* / pathology