Advancements in diagnostic techniques for scorpion venom identification: A comprehensive review

Toxicon. 2024 Nov 28:253:108191. doi: 10.1016/j.toxicon.2024.108191. Online ahead of print.

Abstract

Scorpion envenomation's ignored public health problem in tropical and subtropical countries is alarming. Particularly dangerous for small children and the elderly, it can cause severe problems and even death. Recent studies have proposed the creation of rapid, easy, species-specific, and sensitive detection kits as an alternative to the methods currently used to identify scorpions. Unfortunately, there is currently no commercially available technology for detecting scorpion envenomation in clinical settings, especially in remote tropical health centres. This study delineates the most dangerous scorpion species globally and the advancements in identifying their stings in vitro or in envenomed plasma. Furthermore, we have highlighted the practical challenges associated with scorpion venom detection and the necessity for innovative, expedited, and more accessible detection kits in countries where scorpion envenomation poses a significant issue.

Keywords: Dangerous scorpion species; Detection of scorpion venom toxins; Immunodiagnostic methods; Scorpion envenomation; Scorpion venom detection.

Publication types

  • Review