This study was to investigate the clinical features of chronic obstructive pulmonary disease (COPD) patients with concurrent acute myocardial infarction (AMI) and analyze the occurrence of in-hospital adverse events. Patients with AMI who were admitted to Beijing Chaoyang Hospital from January 2019 to August 2023 were retrospectively collected. All patients were divided into COPD with concurrent AMI group and simple AMI group according to whether they were with concurrent COPD. All patients received interventional treatment for AMI. The clinical features and the occurrence of in-hospital adverse events were compared between the two groups. A total of 183 AMI patients aged (65.6±13.6) years were enrolled, including 142 males (77.6%). There were 94 patients (51.4%) in simple AMI group and 89 patients (48.6%) in COPD with concurrent AMI group, respectively. Patients in COPD with concurrent AMI group were older, had higher Killip grade, rate of smoking and previous percutaneous coronary intervention history, creatinine and B-type natriuretic peptide levels, and lower albumin, hemoglobin, low-density lipoprotein cholesterol, white blood cell count and cardiac troponin I than those of simple AMI group (all P<0.05). There were no significant differences in echocardiographic parameters between the two groups (all P>0.05). The proportion of β-blockers, angiotensin-converting enzyme inhibitors/angiotensin-blockers used in COPD with concurrent AMI group was lower (P<0.05). Patients in COPD with concurrent AMI group had longer length of hospital stay than those in simple AMI group (P=0.028). The incidence of primary endpoint events in COPD with concurrent AMI group was higher than that in simple AMI group (27.0% vs 18.0%, P=0.002). The current study indicates that COPD patients with concurrent AMI have longer length of hospital stay and higher incidence of in-hospital events, which are worthy of significant attention in clinical practice.
探讨慢性阻塞性肺疾病（COPD）合并急性心肌梗死（AMI）患者的临床特征，并分析其院内不良事件发生情况。回顾性收集2019年1月至2023年8月就诊于北京朝阳医院的AMI的患者183例，根据是否合并COPD，分为COPD合并AMI组和单纯AMI组，所有患者均行介入治疗处理AMI。比较两组患者的临床特征及院内不良事件发生情况。183例AMI患者，年龄（65.6±13.6）岁，男142例（77.6%）。单纯AMI组94例（51.4%），COPD合并AMI组89例（48.6%）。与单纯AMI组相比，COPD合并AMI组患者年龄更大，Killip分级、吸烟及既往接受冠脉支架植入术比例、肌酐及B型钠尿肽水平更高，白蛋白、血红蛋白、低密度脂蛋白胆固醇、白细胞计数、心肌肌钙蛋白I更低（均P<0.05）。两组间超声心动图参数差异无统计学意义（均P>0.05）。COPD合并AMI组患者β受体阻滞剂、血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂类药物使用比例更低（P<0.05）。COPD合并AMI组患者住院时间长于单纯AMI组（P=0.028）。COPD合并AMI组患者主要终点事件发生率高于单纯AMI组（27.0%比18.0%，P=0.002）。COPD合并AMI患者住院时间更长，院内事件发生率更高，临床应给予高度重视。.