Matrix metalloprotease-7 is associated with post-COVID-19 persistent lung abnormalities

Ivette Buendia-Roldan; Leslie Chavez-Galan; Hiram Aguilar-Duran; Andy Ruiz; Ramcés Falfan-Valencia; Gloria Pérez-Rubio; Annie Pardo; Moisés Selman

doi:10.1183/23120541.00266-2024

Matrix metalloprotease-7 is associated with post-COVID-19 persistent lung abnormalities

ERJ Open Res. 2024 Dec 2;10(6):00266-2024. doi: 10.1183/23120541.00266-2024. eCollection 2024 Nov.

Authors

Ivette Buendia-Roldan^{1

2}, Leslie Chavez-Galan^{1

2}, Hiram Aguilar-Duran¹, Andy Ruiz¹, Ramcés Falfan-Valencia¹, Gloria Pérez-Rubio¹, Annie Pardo³, Moisés Selman¹

Affiliations

¹ Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City, Mexico.
² I. Buendia-Roldan and L. Chavez-Galan contributed equally.
³ Facultad de Ciencias, Universidad Nacional Autónoma de México, Mexico City, Mexico.

Abstract

This study indicates that increased MMP-7 in patients with post-COVID-19 is associated with lung abnormalities in gas exchange and subtle structural alterations in HRCT suggestive of fibrosis. https://bit.ly/4etsvk5.