Nasal Mucus Cytokines Are Correlated with Spirometry Measures in CRS Patients with Comorbid Asthma

Rory J Lubner; Christina Dorismond; Mason Krysinski; Ping Li; Rakesh K Chandra; Justin H Turner; Dawn C Newcomb; Katherine N Cahill; Naweed I Chowdhury

doi:10.1002/alr.23492

Nasal Mucus Cytokines Are Correlated with Spirometry Measures in CRS Patients with Comorbid Asthma

Int Forum Allergy Rhinol. 2024 Dec 3. doi: 10.1002/alr.23492. Online ahead of print.

Authors

Rory J Lubner¹, Christina Dorismond¹, Mason Krysinski¹, Ping Li¹, Rakesh K Chandra¹, Justin H Turner², Dawn C Newcomb³, Katherine N Cahill⁴, Naweed I Chowdhury¹

Affiliations

¹ Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
² Department of Otolaryngology-Head and Neck Surgery, University of Alabama-Birmingham, Birmingham, Alabama, USA.
³ Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
⁴ Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, Tennessee, USA.

PMID: 39624918
DOI: 10.1002/alr.23492

Abstract

CRS patients with asthma show differential nasal mucus cytokine signatures based on endotype. IL-7 concentration is positively associated with higher %FEV1 and %FVC in CRS patients with asthma.

Keywords: asthma; chronic rhinosinusitis; cytokine; endoscopic sinus surgery.

Abstract

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