Faecal transplantation: the good, the bad and the ugly

Hiu C L Sin; Craig Haifer

doi:10.1111/imj.16559

Faecal transplantation: the good, the bad and the ugly

Intern Med J. 2024 Dec 4. doi: 10.1111/imj.16559. Online ahead of print.

Authors

Hiu C L Sin¹, Craig Haifer^{1

2}

Affiliations

¹ Department of Gastroenterology, St Vincent's Hospital Sydney, Sydney, New South Wales, Australia.
² School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.

PMID: 39629909
DOI: 10.1111/imj.16559

Abstract

There continues to be significant interest from both clinicians and patients in using faecal transplantation, as the integral role of the gut microbiome is increasingly recognised in various disease conditions, both within and beyond the gut. This Clinical Perspectives article provides an overview of existing literature, factors limiting the use of faecal microbial transplantation in clinical practice and exciting new advancements on the horizon.

Keywords: faecal microbiota transplantation; gastrointestinal microbiome; immune checkpoint inhibitors; inflammatory bowel diseases; ulcerative colitis.