Task-Dependent Mechanisms Underlying Prolonged Low-Frequency Force Depression

Exerc Sport Sci Rev. 2025 Jan 1;53(1):41-47. doi: 10.1249/JES.0000000000000352. Epub 2024 Nov 4.

Abstract

Prolonged low-frequency force depression (PLFFD) is an intramuscular phenomenon involving the slow recovery of submaximal muscle strength following strenuous exercise. We hypothesize that the contribution of impaired excitation-contraction coupling processes to PLFFD is task dependent, and that they will be different between metabolically and mechanically demanding exercises. We also discuss evidence of the effectiveness of interventions to mitigate PLFFD.

Publication types

  • Review

MeSH terms

  • Excitation Contraction Coupling / physiology
  • Exercise* / physiology
  • Exercise* / psychology
  • Humans
  • Muscle Contraction / physiology
  • Muscle Fatigue / physiology
  • Muscle Strength* / physiology
  • Muscle, Skeletal* / physiology