Cephalexin--a new oral antibiotic

Postgrad Med J. 1970 Mar;46(533):157-8. doi: 10.1136/pgmj.46.533.157.

Abstract

The pharmacology, antimicrobial activity and clinical uses of cephalexin, a semi-synthetic derivative of cephalosporin C, are described.

Cephalexin is active, when taken by mouth, against Gram-positive cocci, including penicillinase-producing staphylococci, and against many Gram-negative organisms including Gram-negative rods.

There is a low incidence of side effects.

Publication types

  • Review

MeSH terms

  • Animals
  • Cephalosporins / adverse effects
  • Cephalosporins / pharmacology
  • Cephalosporins / therapeutic use*
  • Gonorrhea / drug therapy
  • Humans
  • Penicillinase / biosynthesis
  • Respiratory Tract Infections / drug therapy
  • Sepsis / drug therapy
  • Staphylococcal Infections / drug therapy
  • Staphylococcus / drug effects
  • Staphylococcus / metabolism
  • Urinary Tract Infections / drug therapy

Substances

  • Cephalosporins
  • Penicillinase