6-Chlorochroman-2-carboxylic acids. Synthesis and biological evaluation as antagonists for cholesterol biosynthesis and lipolysis in vitro

J Med Chem. 1971 Aug;14(8):758-66. doi: 10.1021/jm00290a021.
No abstract available

MeSH terms

  • Adipose Tissue / metabolism
  • Animals
  • Anticholesteremic Agents / pharmacology
  • Benzopyrans / administration & dosage
  • Benzopyrans / chemical synthesis*
  • Benzopyrans / pharmacology*
  • Carbon Isotopes
  • Carboxylic Acids / administration & dosage
  • Carboxylic Acids / chemical synthesis
  • Carboxylic Acids / pharmacology
  • Depression, Chemical
  • Epididymis / metabolism
  • Glycerol / metabolism
  • Hypolipidemic Agents / pharmacology
  • Magnetic Resonance Spectroscopy
  • Male
  • Mevalonic Acid / metabolism
  • Norepinephrine / metabolism
  • Polymers
  • Rats

Substances

  • Anticholesteremic Agents
  • Benzopyrans
  • Carbon Isotopes
  • Carboxylic Acids
  • Hypolipidemic Agents
  • Polymers
  • Glycerol
  • Mevalonic Acid
  • Norepinephrine