Terferol, an inhibitor of cyclic adenosine 3',5'-monophosphate phosphodiesterase. II. Structural elucidation

F Nakagawa; S Takahashi; A Naito; S Sato; S Iwabuchi; C Tamura

doi:10.7164/antibiotics.37.10

Terferol, an inhibitor of cyclic adenosine 3',5'-monophosphate phosphodiesterase. II. Structural elucidation

J Antibiot (Tokyo). 1984 Jan;37(1):10-2. doi: 10.7164/antibiotics.37.10.

Authors

F Nakagawa, S Takahashi, A Naito, S Sato, S Iwabuchi, C Tamura

PMID: 6321422
DOI: 10.7164/antibiotics.37.10

Abstract

Streptomyces showdoensis SANK 65080 produced terferol, an inhibitor of cyclic adenosine 3',5'-monophosphate phosphodiesterase (cAMP-PDE). NMR spectrometry and X-ray analysis were used to determine the structure of the compound, a new member of the terphenyl family.

MeSH terms

3',5'-Cyclic-AMP Phosphodiesterases / antagonists & inhibitors*
Crystallography
Magnetic Resonance Spectroscopy
Models, Molecular
Streptomyces / analysis
Terphenyl Compounds / analysis*
X-Rays

Substances

Terphenyl Compounds
terferol
3',5'-Cyclic-AMP Phosphodiesterases