[Effect of a new synthetic cyclic-nucleoside on cell proliferation]

Rev Esp Oncol. 1983;30(4):525-31.
[Article in Spanish]

Abstract

The activity of a new synthetic C-nucleoside upon cell proliferation was tested using mouse Ehrlich ascites tumor cells and PHA-stimulated human blood T lymphocytes. The product did not modify the cancer cells reproduction. Contrarily, it inhibited T lymphocytes proliferation.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology*
  • Carcinoma, Ehrlich Tumor / pathology*
  • Cell Division / drug effects
  • Humans
  • In Vitro Techniques
  • Indolequinones*
  • Mice
  • Nucleosides / pharmacology
  • T-Lymphocytes / drug effects*

Substances

  • Antineoplastic Agents
  • Indolequinones
  • Nucleosides
  • 6,6-dimethyl-2-erythrofuranosyl-4,5,6,7-tetrahydroindol-4-one