Diagnosis of acute inflammatory conditions in children and adolescents using In-111 oxine white blood cells

Clin Nucl Med. 1984 Feb;9(2):71-4. doi: 10.1097/00003072-198402000-00003.

Abstract

In-111 oxine labeled white cells were used to diagnose acute inflammatory conditions in 42 children and adolescents, aged 6 weeks to 19 years. In 43 scans where a clinical correlation could be made, the test had a sensitivity of 81% and a specificity of 94%. There were no adverse reactions. For children the dose of In-111 recommended is 10-12 mu Ci/kg body weight to a maximum of 500 mu Ci.

MeSH terms

  • Abscess / diagnostic imaging*
  • Acute Disease
  • Adolescent
  • Adult
  • Arthritis, Infectious / diagnostic imaging*
  • Child
  • Child, Preschool
  • False Negative Reactions
  • Female
  • Humans
  • Hydroxyquinolines*
  • Indium*
  • Infant
  • Leukocytes*
  • Male
  • Organometallic Compounds*
  • Oxyquinoline* / analogs & derivatives
  • Radiation Dosage
  • Radioisotopes*
  • Radionuclide Imaging

Substances

  • Hydroxyquinolines
  • Organometallic Compounds
  • Radioisotopes
  • Indium
  • indium oxine
  • Oxyquinoline