[Blood T lymphocyte populations in the hemophiliac]

Rev Fr Transfus Immunohematol. 1984 Sep;27(4):473-7. doi: 10.1016/s0338-4535(84)80144-0.
[Article in French]

Abstract

We have studied a group of 31 hemophiliac patients (hemophilia A: 26 patients, hemophilia B: 5 patients); 29 healthy men were used as controls. Hemophiliac patients had increased percentages of suppressor T-lymphocytes and depressed T4/T8 ratios. These abnormalities were found to be significantly correlated with the amount of F VIII used per year.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Blood Transfusion
  • Child
  • Child, Preschool
  • Factor VIII / therapeutic use
  • Female
  • Hemophilia A / blood*
  • Hemophilia A / therapy
  • Humans
  • Male
  • Middle Aged
  • T-Lymphocytes / classification*

Substances

  • Factor VIII