[Calculi experimentally obtained in the rat by intrarenal injection of Ureaplasma urealyticum]

Ann Biol Clin (Paris). 1984;42(4):277-81.
[Article in French]

Abstract

Male Sprague Dawley rats have been contaminated with Ureaplasma urealyticum (by injection in their kidney of a 10(8) C.C.U. suspension of micro-organisms of human origin). They produce urinary tract stones similar to the humans ones and composed of struvite crystals (NH4MgPO4, 6H2O). It is concluded that such a model is a very good tool to develop new research on struvite lithiasis.

Publication types

  • Comparative Study
  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chemical Phenomena
  • Chemistry
  • Disease Models, Animal
  • Injections
  • Kidney
  • Male
  • Rats
  • Rats, Inbred Strains
  • Spectrophotometry, Infrared
  • Ureaplasma / pathogenicity*
  • Urinary Bladder Calculi / etiology*
  • X-Ray Diffraction