Abstract
A case is described of a 47-year-old man who developed a manic psychosis while receiving pargyline treatment for concurrent depression and hypertension. The pharmacologic actions of pargyline are discussed with regard to its partial selectivity for MAO-B and presumed action in dopamine systems, and clinicians are alerted to this uncommon drug reaction.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Affective Disorders, Psychotic / chemically induced*
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Bipolar Disorder / chemically induced*
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Depressive Disorder / complications
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Depressive Disorder / drug therapy*
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Depressive Disorder / psychology
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Humans
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Hypertension / complications
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Hypertension / drug therapy*
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Male
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Middle Aged
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Pargyline / adverse effects*
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Pargyline / pharmacology
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Pargyline / therapeutic use