In an attempt to determine the clinical significance of taurodontism, two reports of cases of patients with the anomaly have been presented. It seems that the taurodont form does not interfere with routine operative procedures, but it is suggested that the morphology might hamper the location of orifices and could create difficulties in instrumentation and obturation in endodontic treatment. It is hoped that other cases involving the treatment of taurodont teeth will be reported to aid in determining the clinical significance of the anomaly for other areas of dentistry.