Combined radiotherapy and chemotherapy with cyclophosphamide, adriamycin, methotrexate, procarbazine (CAMP) in 64 consecutive patients with epidermoid bronchogenic carcinoma, limited disease: a prospective study

Int J Radiat Oncol Biol Phys. 1982 Jun;8(6):1051-4. doi: 10.1016/0360-3016(82)90176-6.

Abstract

Sixty-four consecutive patients with inoperable epidermoid bronchogenic carcinoma (limited disease) were treated with radiotherapy to the primary and nodal areas and combination chemotherapy with cyclophosphamide, adriamycin, methotrexate and procarbazine. The overall response rate (CR + PR) to combined treatment was 62%. The median survival time was 12.7 months. The toxicity was acceptable and no treatment-related death occurred.

MeSH terms

  • Adult
  • Aged
  • Carcinoma, Bronchogenic / drug therapy
  • Carcinoma, Bronchogenic / radiotherapy*
  • Carcinoma, Squamous Cell / drug therapy
  • Carcinoma, Squamous Cell / radiotherapy*
  • Cyclophosphamide / therapeutic use*
  • Doxorubicin / therapeutic use*
  • Drug Administration Schedule
  • Drug Therapy, Combination
  • Female
  • Follow-Up Studies
  • Humans
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / radiotherapy*
  • Male
  • Methotrexate / therapeutic use*
  • Middle Aged
  • Procarbazine / therapeutic use*
  • Prognosis
  • Radiotherapy Dosage

Substances

  • Procarbazine
  • Doxorubicin
  • Cyclophosphamide
  • Methotrexate