GYKI 14,451, a synthetic tripeptide inhibitor of thrombin: activity on platelet aggregation and arachidonic acid metabolism

Pharmacol Res Commun. 1981 Apr;13(4):339-49. doi: 10.1016/s0031-6989(81)80004-5.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arachidonic Acids / metabolism*
  • Humans
  • Kinetics
  • Malondialdehyde / metabolism
  • Oligopeptides / pharmacology*
  • Peptides / pharmacology*
  • Platelet Aggregation / drug effects*
  • Thrombin / antagonists & inhibitors*
  • Thromboxane A2 / biosynthesis

Substances

  • Arachidonic Acids
  • Oligopeptides
  • Peptides
  • Malondialdehyde
  • Thromboxane A2
  • tert-butyloxycarbonyl-phenylalanyl-prolyl-arginal
  • Thrombin