Depressed hepatic dihydropyrimidine dehydrogenase activity and fluorouracil-related toxicities

Am J Med. 1995 Dec;99(6):685-8. doi: 10.1016/s0002-9343(99)80259-9.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / enzymology
  • Adult
  • Antimetabolites, Antineoplastic / adverse effects*
  • Antimetabolites, Antineoplastic / metabolism
  • Brain Diseases / chemically induced*
  • Brain Diseases / enzymology
  • Cecal Neoplasms / enzymology
  • Dihydrouracil Dehydrogenase (NADP)
  • Female
  • Fluorouracil / adverse effects*
  • Fluorouracil / metabolism
  • Humans
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / enzymology*
  • Liver Neoplasms / secondary
  • Oxidoreductases / metabolism*
  • Tumor Lysis Syndrome / enzymology
  • Tumor Lysis Syndrome / etiology*

Substances

  • Antimetabolites, Antineoplastic
  • Oxidoreductases
  • Dihydrouracil Dehydrogenase (NADP)
  • Fluorouracil