Extramammary Paget's disease associated with prostate adenocarcinoma

Hum Pathol. 1994 Jun;25(6):615-7. doi: 10.1016/0046-8177(94)90229-1.

Abstract

A case of scrotal and penile extramammary Paget's disease (EMPD) and concurrent prostate adenocarcinoma in a 59-year-old patient is presented. Immunohistochemically, the tumor cells of both the EMPD and prostate stained positively for prostate-specific antigen. Six previously reported cases of EMPD associated with prostate adenocarcinoma are reviewed, along with a discussion of current theories of the pathogenesis of EMPD.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma / pathology*
  • Carcinoembryonic Antigen / analysis
  • Genital Neoplasms, Male / pathology*
  • Humans
  • Male
  • Middle Aged
  • Neoplasms, Multiple Primary / pathology*
  • Paget Disease, Extramammary / pathology*
  • Prostate-Specific Antigen / analysis
  • Prostatic Neoplasms / pathology*
  • S100 Proteins / analysis

Substances

  • Carcinoembryonic Antigen
  • S100 Proteins
  • Prostate-Specific Antigen