Structure-function relationships of human alpha 2-macroglobulin. Three-dimensional structures of native alpha 2-macroglobulin and its methylamine and chymotrypsin derivatives

Ann N Y Acad Sci. 1994 Sep 10:737:212-28. doi: 10.1111/j.1749-6632.1994.tb44314.x.
No abstract available

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Binding Sites
  • Chymotrypsin / metabolism
  • Chymotrypsin / ultrastructure*
  • Esters / metabolism
  • Humans
  • Image Processing, Computer-Assisted
  • Methylamines / pharmacology*
  • Microscopy, Electron
  • Models, Molecular
  • Molecular Conformation
  • Protease Inhibitors* / metabolism
  • Structure-Activity Relationship
  • Sulfhydryl Compounds / metabolism
  • alpha-Macroglobulins / drug effects
  • alpha-Macroglobulins / metabolism
  • alpha-Macroglobulins / ultrastructure*

Substances

  • Esters
  • Methylamines
  • Protease Inhibitors
  • Sulfhydryl Compounds
  • alpha-Macroglobulins
  • methylamine
  • Chymotrypsin