Low CD4 lymphocyte count in a patient with P. carinii pneumonia after autologous bone marrow transplantation

E Castagnola; G Dini; E Lanino; L Tasso; S Dallorso; A Garaventa; G A Rossi; R Giacchino

Low CD4 lymphocyte count in a patient with P. carinii pneumonia after autologous bone marrow transplantation

Bone Marrow Transplant. 1995 Jun;15(6):977-8.

Authors

E Castagnola¹, G Dini, E Lanino, L Tasso, S Dallorso, A Garaventa, G A Rossi, R Giacchino

Affiliation

¹ Department of Infectious Diseases, G Gaslini Children's Hospital, Genova, Italy.

PMID: 7581100

Abstract

Authors report a case of P. carinii pneumonia in a child with 5% CD4 lymphocytes (absolute number 5/microliters) after autologous bone marrow transplantation followed by pulmonary irradiation. Serial evaluation of CD4 lymphocyte count or percentage or, at least, detection of significant and persistent lymphopenia could be useful for detecting a high risk of developing P. carinii pneumonia.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Bone Marrow Transplantation / immunology*
CD4 Lymphocyte Count*
Child, Preschool
Combined Modality Therapy
Disease Susceptibility
Fatal Outcome
Female
Humans
Immunocompromised Host*
Lung Neoplasms / drug therapy
Lung Neoplasms / radiotherapy
Lung Neoplasms / secondary
Neuroectodermal Tumors, Primitive, Peripheral / drug therapy
Neuroectodermal Tumors, Primitive, Peripheral / radiotherapy
Neuroectodermal Tumors, Primitive, Peripheral / secondary
Neuroectodermal Tumors, Primitive, Peripheral / therapy
Pneumonia, Pneumocystis / immunology*
Pulmonary Fibrosis / etiology
Radiotherapy / adverse effects*
Retroperitoneal Neoplasms / drug therapy
Retroperitoneal Neoplasms / therapy