The effect of newer generation lithotripsy upon renal function assessed by nuclear scintigraphy

J Urol. 1995 Sep;154(3):947-50.

Abstract

Purpose: We studied the effect of second generation lithotripsy on renal function.

Materials and methods: We evaluated 42 patients with unilateral renal calculi by nuclear renography, serum creatinine levels, renal ultrasonography and plain radiographs.

Results: There was no significant change in glomerular filtration rate at 1 or 3 months. Split function of the treated kidneys was lower at 1 month (mean 47.2%, p = 0.01) and 3 months (47.3%, p = 0.01) than before treatment (49.1%). A greater than 5% decrease in split function of the treated kidney occurred at 1 month in 6 patients (16.2%) and at 3 months in 3. Of the patients 23 (62.2%) were stone-free and 11 had residual fragments less than 4 mm., with a 19% retreatment rate for an overall success rate of 91.9%.

Conclusions: Newer generation lithotriptors may limit renal damage while permitting satisfactory treatment of renal calculi.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Adult
  • Creatinine / blood
  • Female
  • Glomerular Filtration Rate
  • Humans
  • Kidney / diagnostic imaging
  • Kidney Calculi / diagnostic imaging*
  • Kidney Calculi / physiopathology
  • Lithotripsy* / adverse effects
  • Male
  • Middle Aged
  • Prospective Studies
  • Radiography
  • Radioisotope Renography*

Substances

  • Creatinine