Antipsychotic drugs and tardive dyskinesia: preliminary results in an adolescent psychiatric ward

J Clin Pharm Ther. 1995 Apr;20(2):63-5. doi: 10.1111/j.1365-2710.1995.tb00630.x.

Abstract

The systematic study of antipsychotic-induced movement disorders in young psychiatric patients is very sparse. We assessed the presence of tardive dyskinesia in an adolescent in-patient psychiatric ward. Eighteen per cent (3/17) exhibited either pronounced or subtle signs of tardive dyskinesia. Our study suggests that young psychiatric patients may develop signs of tardive dyskinesia even though they are exposed to relatively short-term neuroleptic treatment and at dosages that are relatively low. We advocate frequent and systematic monitoring of adolescent patients taking antipsychotic drugs in order to minimize the emergence of this long-term, troublesome complication of neuroleptic drugs.

MeSH terms

  • Adolescent
  • Adult
  • Antiparkinson Agents / adverse effects
  • Antiparkinson Agents / therapeutic use
  • Antipsychotic Agents / administration & dosage
  • Antipsychotic Agents / adverse effects*
  • Antipsychotic Agents / therapeutic use
  • Dose-Response Relationship, Drug
  • Drug Monitoring
  • Drug Synergism
  • Dyskinesia, Drug-Induced / etiology*
  • Female
  • Humans
  • Male
  • Sex Factors

Substances

  • Antiparkinson Agents
  • Antipsychotic Agents