Diffuse Lewy body disease as substrate of primary lateral sclerosis

J Neurol. 1995 Jan;242(2):59-63. doi: 10.1007/BF00887816.

Abstract

We describe the case of a 40-year-old male patient who had presented clinically as primary lateral sclerosis for the past 10 years and neuropathologically as diffuse Lewy body disease (DLBD). Neuropathology demonstrated DLBD as an almost ubiquitous disorder of the neuronal cytoskeleton.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amyotrophic Lateral Sclerosis / etiology
  • Amyotrophic Lateral Sclerosis / pathology*
  • Fatal Outcome
  • Humans
  • Lewy Bodies / ultrastructure
  • Male
  • Neurofilament Proteins / analysis
  • Parkinson Disease / complications
  • Parkinson Disease / pathology*
  • Ubiquitins / analysis
  • tau Proteins / analysis

Substances

  • Neurofilament Proteins
  • Ubiquitins
  • tau Proteins