Studies of the coding region of the neuronal glutamate transporter gene in amyotrophic lateral sclerosis

Ann Neurol. 1995 Jun;37(6):817-9. doi: 10.1002/ana.410370618.

Abstract

Studies of the coding region of the neuronal glutamate transporter of 6 amyotrophic lateral sclerosis (ALS) patients and 10 controls show an identical pattern of four reported amino acid variations. No mutations and polymorphisms were detected in 5 sporadic ALS patients and a single patient with the familial form of the disease.

MeSH terms

  • ATP-Binding Cassette Transporters / genetics*
  • Amino Acid Transport System X-AG
  • Amyotrophic Lateral Sclerosis / genetics*
  • Base Sequence
  • Genes
  • Genetic Code
  • Humans
  • Molecular Sequence Data
  • Neurons / physiology

Substances

  • ATP-Binding Cassette Transporters
  • Amino Acid Transport System X-AG