Eight infants with stage 3+ retinopathy of prematurity (ROP) were treated using the diode laser through a binocular indirect ophthalmoscope. Two infants with zone I disease were treated prethreshold as soon as the signs of plus disease developed. Successful regression was achieved in all cases, though 3 infants required repeat treatment. All infants were followed up for a minimum of 3 months. Keeler acuity scores were in the normal range in 4 of the 8 infants.