[Direct approach for demonstrating free radical phenomena during equine postanesthetic myopathy: preliminary study]

Can J Vet Res. 1994 Oct;58(4):309-12.
[Article in French]

Abstract

This preliminary study demonstrated the existence of a free radical generation during an experimental postischemic muscular reperfusion in a halothane anesthetized horse. The authors used alpha-phényl-N-tert-butylnitrone as a spin trap agent and the electronic paramagnetic resonance method to observe in vivo a free radical generation.

Publication types

  • English Abstract

MeSH terms

  • Anesthesia, Inhalation / adverse effects
  • Anesthesia, Inhalation / veterinary*
  • Animals
  • Cyclic N-Oxides
  • Female
  • Free Radicals / metabolism*
  • Halothane / adverse effects
  • Horse Diseases / etiology
  • Horse Diseases / metabolism*
  • Horses
  • Muscular Diseases / metabolism
  • Muscular Diseases / veterinary*
  • Nitrogen Oxides
  • Reperfusion Injury / metabolism
  • Reperfusion Injury / veterinary*
  • Spin Labels

Substances

  • Cyclic N-Oxides
  • Free Radicals
  • Nitrogen Oxides
  • Spin Labels
  • phenyl-N-tert-butylnitrone
  • Halothane