Peptic ulcer disease in the elderly in Singapore

J Gastroenterol Hepatol. 1994 May-Jun;9(3):278-81. doi: 10.1111/j.1440-1746.1994.tb01725.x.

Abstract

Of 460 patients with peptic ulcer disease seen over a 30-month period, there were 174 elderly patients (defined as > or = 60 years old), constituting 38%. In this group of elderly, gastric ulcers (GU) were observed more frequently than duodenal ulcers (DU) with a ratio of 1.6:1 and the male to female ratio was 1.7:1. In patients < 60 years old, there were more DU than GU with a ratio of 2.7:1, and a higher male to female ratio of 3.7:1. Seventy-two per cent of the elderly had at least one other medical condition with 20% having three or more medical problems. Hypertension and ischaemic heart disease were the most frequently encountered illnesses. Half the elderly presented with upper abdominal pain and one-third had an atypical presentation. Analgesic ingestion in the preceding 4 weeks was present in 29% of the elderly. In the elderly, bleeding was the most frequent complication occurring in 50%; perforation occurred in 2%. In those with bleeding ulcers, 44% had history of analgesic usage. The mortality of bleeding peptic ulcer in the elderly, was 11% and this was largely due to concurrent medical conditions. Only two deaths occurred due to bleeding ulcer.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Demography
  • Duodenal Ulcer / epidemiology
  • Female
  • Gastrointestinal Hemorrhage / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Peptic Ulcer / epidemiology*
  • Prognosis
  • Singapore / epidemiology
  • Stomach Ulcer / epidemiology