Objectives: To assess the diagnostic yield of the 1-yr follow-up flexible sigmoidoscopy examination for the detection of colonic neoplasia in a colorectal cancer screening program.
Methods: Data were prospectively collected for flexible sigmoidoscopies performed between July 1991 and July 1992 as part of the University of South Alabama Colon Cancer Registry.
Results: A total of 217 subjects with an age-related risk of colon carcinoma and no evidence of occult blood by stool examination were enrolled. One hundred and sixteen underwent initial sigmoidoscopic examination, and 101 had a 1-yr surveillance examination. Ten of the 116 patients (8.6%) undergoing initial surveillance sigmoidoscopy were found to have neoplastic lesions. In contrast, only 1/101 (1%) patients undergoing 1-yr follow-up surveillance sigmoidoscopy was found to have a neoplastic lesion. Neoplastic lesions in both groups were adenomas. No carcinomas were found.
Conclusions: These data suggest that the 1-yr surveillance sigmoidoscopy adds little to the diagnostic yield of colon cancer screening.